Re-Growing Frog’s Lost Limb (E)

Researchers from Tufts University and Harvard University have succeeded in re-growing a frog’s lost limb. The researchers triggered the regenerative process in the African clawed frog by enclosing the wound in a silicone cap containing a silk protein gel, loaded with five-drug cocktail. Each drug in this cocktail fulfilled a different purpose, from reducing inflammation to helping with the development of nerve fibres, blood vessels, and muscles. The Bio-Dome was sealed for 24 hours, which triggered the process of regeneration, followed by almost complete restoration of the frog’s functional limb at 18 months. This breakthrough has brought the medical science closer to the goal of regenerative medicine.

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